Invitrogen™ FGFR4 Monoclonal Antibody (4H2B10B2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515350

Catalog No. PIMA515350

Description

MA5-15350 targets FGFR4 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15350 immunogen is purified recombinant fragment of FGFR4 expressed in E. Coli. MA5-15350 detects FGFR4 which has a predicted molecular weight of approximately 88kDa.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.

Specifications

• Antigen: FGFR4
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P22455
• Gene Symbols: Fgfr4
• Immunogen: Purified recombinant fragment of FGFR4 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 2264
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4H2B10B2
• Conjugate: Unconjugated
• Gene: Fgfr4
• Gene Alias: CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1