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Invitrogen™ FGFR5 Polyclonal Antibody
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Catalog No. PIPA521516
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PIPA521516 100 μL
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Catalog No. PIPA521516 Supplier Invitrogen™ Supplier No. PA521516
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, HepG2 membrane extract, FGFRL1-transfected 293T. Predicted reactivity: Mouse (88%), Rat (89%), Bovine (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuro-ectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. A total of six members of the FGF receptor family have been identified and cloned. These include the Flg receptor or FGFR-1, the BEK receptor or FGFR-2, FGFR-3, FGFR-4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. However, FGFR-5 lacks the cytoplasmic kinase domain. FGFR-5 is expressed in a broad range of tissues, including kidney, brain and lung, but it is preferentially expressed in pancreas, where it may play a role in the regulation of some pancreatic function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene FGFRL1
Gene Accession No. Q8N441
Gene Alias alpha-L-iduronidase; FGF homologous factor receptor; FGF receptor-like protein 1; Fgfr5; FGFR-5; FGFR5beta; FGFR5gamma; Fgfrl1; FGFR-like protein; FHFR; fibroblast growth factor receptor 5; Fibroblast growth factor receptor-like 1; fibroblast growth factor receptor-like protein; UNQ480/PRO943
Gene Symbols FGFRL1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human FGFR5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53834
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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