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FGIN-1-27, Tocris Bioscience™

Catalog No. 065810
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Catalog No. Quantity
06-581-0 10 mg
06-585-0 50 mg
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Catalog No. 06-581-0 Supplier R&D Systems Supplier No. 0658/10
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Description

Potent, specific ligand for mitochondrial DBI receptor

Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.

Chemical Identifiers

CAS 142720-24-9
Molecular Formula C28H37FN2O
Molecular Weight (g/mol) 436.615
InChI Key VUWXAQFLTSBUDB-UHFFFAOYSA-N
Synonym fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658
PubChem CID 132496
IUPAC Name 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
SMILES CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F

Specifications

Quantity 10 mg
Formula Weight 436.61
Percent Purity >98%
Chemical Name or Material FGIN-1-27

Safety and Handling

Recommended Storage Store at Room Temperature
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