Invitrogen™ Fibrinogen gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529734

Catalog No. PIPA529734

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, human plasma, HepG2 sup., Mouse plasma. Predicted reactivity: Mouse (92%), Rat (91%), Pig (88%), Chicken (81%), Bovine (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

• Antigen: Fibrinogen gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fgg
• Gene Alias: 3010002H13Rik; AI256424; FGG; fibg; fibrinogen; fibrinogen gamma chain; Fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, gamma polypeptide; gamma'; gamma-fibrinogen; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.39 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P02679
• Gene Symbols: Fgg
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Fibrinogen gamma. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG