Invitrogen™ Fibrinogen Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA19526

Catalog No. 01-674-409

Description

PA1-9526 detects Fibrinogen in human samples. PA1-9526 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9526 detects a ~94 kDa protein representing Fibrinogen. The PA1-9526 immunogen is a mixture of synthetic peptides based on human fibrinogen.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

Specifications

• Antigen: Fibrinogen
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FGG
• Gene Alias: 2510049G14Rik; 3010002H13Rik; A-alpha fibrinogen; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; carboxy-terminal region; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; Fga; Fgb; Fgg; Fib; Fib2; fibg; fibrinogen; fibrinogen A-alpha chain; fibrinogen A-alpha-chain; fibrinogen alpha chain; fibrinogen alpha-E subunit; fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma polypeptide; fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; Gamma'; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Chicken
• Purification Method: IgY fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 2243, 2244, 2266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P02671, P02675, P02679
• Gene Symbols: FGA, FGB, FGG
• Immunogen: Mixture of synthetic peptides based on human fibrinogen.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgY