AdipoGen Fisetin

Supplier:  AdipoGen CDXF0336M500

Chemical. CAS 528-48-3. Formula C15H10O6. MW 286.24. Synthetic. One of the major polyphenolic flavonoids found in various fruits and vegetables such as apples, grapes, persimmons, strawberries, cucumbers and onions. Exerts numerous beneficial biological activities, including antibacterial, antifungal, antioxidant, anti-inflammatory, antiangiogenic, antiproliferative, proapoptotic, cell cycle arrest, autophagy inducing, hypolipidemic, neuroprotective and antitumor effects. Modulates multiple signaling pathways such as blocking of the phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin PI3K/Akt/mTOR and p38, mitogen-activated protein kinases MAPK-dependent nuclear factor kappa-light-chain-enhancer of activated B cells NF-kappaB signaling, Wnt and adrogen receptor signaling, which playing a central role in various cellular processes contributing to the malignancy. Binds to beta-tubulin and disrupts microtubule dynamics.

Catalog No. 50-256-0856