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Invitrogen™ FK506 Monoclonal Antibody (4C12)
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Catalog No. PIMA549653
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200 μg
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Catalog No. Quantity
PIMA549653 200 μg
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Catalog No. PIMA549653 Supplier Invitrogen™ Supplier No. MA549653
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Description

Mouse Monoclonal Antibody

Antibody tested in indirect ELISA.

Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent. [National Center for Biotechnology Information. PubChem Compound Database; CID=445643].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FK506
Applications ELISA, Immunohistochemistry, Lateral Flow, SDS-Page
Classification Monoclonal
Clone 4C12
Concentration 4.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Alias C44H69NO12; FK-506; Fujimycin; Tacrolimus
Host Species Mouse
Immunogen Conjugate of TRL hapten and KLH.
Purification Method Protein G
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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