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  6. Invitrogen™ FKBP4 Recombinant Rabbit Monoclonal Antibody (K01_1R21) 

Invitrogen™ FKBP4 Recombinant Rabbit Monoclonal Antibody (K01_1R21)
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Catalog No. MA563370
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MA563370 100 μL
MA564829 50 μL
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Catalog No. MA563370 Supplier Invitrogen™ Supplier No. MA563370
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Description

Rabbit Recombinant Monoclonal Antibody

FKBP4 Recombinant Monoclonal Antibody for ICC/IF, Western Blot

FKBP4, encoding FK506-binding protein 4, is part of the immunophilin family and plays roles in cellular processes like protein folding and trafficking. The FKBP4 gene is located on chromosome 12, where it encodes a protein involved in modulating the androgen receptor signaling pathway and has been implicated in various cancers, including non-small-cell lung cancer (NSCLC) and hepatocellular carcinoma (HCC). Structural variants of FKBP4 found through exome sequencing have shown potential deleterious effects on protein function. This gene is associated with cell proliferation, apoptosis, migration, and invasion in cancer cells. FKBP4 also influences metabolic processes, such as glycolysis, thereby contributing to cancer cell survival and growth. Importantly, FKBP4 has a role in disorders of sexual development due to its regulatory interaction with hormone signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FKBP4
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone K01_1R21
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 150mM NaCl, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene FKBP4
Gene Accession No. P30416, Q02790, Q9QVC8
Gene Alias 51 kDa FK506-binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; 59kDa; AL022792; AW208983; FK506 binding protein 4; FK506 binding protein 4, 59kDa; FK506 binding protein 52; FK506-binding protein 4; FK506-binding protein 4 (59kD); FKBP prolyl isomerase 4; Fkbp4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52 protein; FKBP59; Fkpb52; HBI; HSP binding immunophilin; Hsp56; hsp90 binding protein; HSP-binding immunophilin; immunophilin FKBP52; p52; P59; p59 protein; peptidylprolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; PPIase; PPIase FKBP4; rotamase; T-cell FK506-binding protein, 59kD
Gene Symbols FKBP4
Host Species Rabbit
Immunogen A synthetic peptide of human FKBP52.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100762395, 14228, 2288, 260321
Target Species Hamster, Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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