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Novus Biologicals™ Flagellin Native Protein
SDP

Catalog No. NB171715
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Quantity:
100 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Native Protein

Binds to human & mouse TLR5. Activation of TLR5 in human epithelial cell assays based on NF-kB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 & matrilysin (MMP-7). Maturation of dendritic cells in in vitro & in vivoassays. Adjuvant activity on foreign antigens delivered by subcutaneous & intranasal routes in mice. TLR5 can be stimulated in vitro by Flagellin 5-50ng/mL & in vivo at a starting concentration of 0.1-1 ug/mouse.)

Specifications

Accession Number P06179
Concentration LYOPH
For Use With (Application) Bioactivity, ELISA
Formulation Lyophilized from PBS
Quantity 100 μg
Storage Requirements Store at 4C short term. Aliquot and Store at -20°C long term. Avoid freeze-thaw cycles.
Endotoxin Concentration <0.1 EU/μg purified protein (LAL test; Lonza).
Reconstitution Reconstitute with 100 ul sterile water (1mg/ml after reconstitution)
Research Category Immunology, Innate Immunity
Purity or Quality Grade >90% SDS-PAGE
Protein Flagellin
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