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Invitrogen™ FLI1 Monoclonal Antibody (7.3)
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Catalog No. MA1196
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100 μL
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MA1196 100 μL
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Catalog No. MA1196 Supplier Invitrogen™ Supplier No. MA1196
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Description

Mouse Monoclonal Antibody

MA1-196 detects FLI-1 in human and mouse samples. MA1-196 has been successfully used in western blot, immunofluorescence and ChIP assays.

The FLI1 (Friend Leukemia Integration 1) gene is located on chromosome 11q24.3 and belongs to the ETS (E26 transformation-specific) family of transcription factors. Structurally, FLI1 contains an ETS domain responsible for DNA binding and a pointed domain which facilitates protein-protein interactions. Functionally, it plays a critical role in the regulation of embryonic and hematopoietic development. It is also implicated in the pathogenesis of diseases such as Ewing's sarcoma, wherein a chromosomal translocation t(11;22)(q24;q12) forms the EWS-FLI1 fusion gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FLI1
Applications ChIP Assay, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7.3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Fli1
Gene Accession No. P26323, Q01543
Gene Alias Ewing sarcoma breakpoint region 2; EWSR2; Fli1; Fli-1; Fli-1 proto-oncogene, ETS transcription factor; Friend leukemia integration 1; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Retroviral integration site protein Fli-1; Sic1; SIC-1; transcription factor ERGB
Gene Symbols Fli1
Host Species Mouse
Immunogen Recombinant human DHFR-FLICTER (C-terminal region of FLI-1) protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14247, 2313
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG3
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