FLJ14213 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 263551AP150UL

Catalog No. 50-173-5314

Description

Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.

Specifications

• Antigen: FLJ14213
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRR5L
• Gene Alias: FLJ14213, Proline rich protein 5 like, Protein observed with Rictor 2, protor 2, PROTOR2, PRR5L
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79899
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q6MZQ0
• Gene Symbols: PRR5L
• Immunogen: FLJ14213 Fusion Protein Ag23837
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG