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Fluorescein disodium salt

Catalog No. AAJ6154922
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Quantity:
100 g
500 g

Fluorescein disodium salt (uranin, fluorescite, acid yellow 73, CAS # 518-45-6) is the salt of the xanthene dye commonly used for fluorescent tracing. | CAS: 518-47-8 | C20H10Na2O5 | 376.28 g/mol

Fluorescein disodium salt is used as fluorescent tracer, has been utilized in studies as a drug model, as a penetrating dye . Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.1 Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.5 Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP). Additional reported uses include microscopy, as a gain medium in dye laser use and to detect latent blood stains in vitro. Common derivatives of Fluorescein include fluorescein isothiocyanate (FITC), eosin and Rose Bengal (sc-296278) and Rose Bengal sodium salt

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Fluorescein disodium salt is a yellow-green phthalate indicator dye that is pH-sensitive

• It has a maximum absorbance of 494nm and maximum emission of 521nm

Application

• Fluorescein disodium salt can be used as a fluorescent protein labeler

• Fluorescein is also useful for the staining of cells and organelles

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 518-47-8
Molecular Formula C20H10Na2O5
Molecular Weight (g/mol) 376.28
MDL Number MFCD00167039
InChI Key NJDNXYGOVLYJHP-UHFFFAOYSA-L
Synonym Acid Yellow 73; C.I. 45350
IUPAC Name disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
SMILES [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=CC(=O)C=C2OC2=CC([O-])=CC=C12

Specifications

Color Brown-Red
Quantity 100 g
Beilstein 3833041
Merck Index 14,4159
Solubility Information Soluble in water at 1mg/ml
Formula Weight 376.28
Physical Form Powder
Chemical Name or Material Fluorescein disodium salt
EINECSNumber 208-253-0
RTECSNumber LM5425000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only

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