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Invitrogen™ FMNL2 Polyclonal Antibody
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PIPA552148 100 μL
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Catalog No. PIPA552148 Supplier Invitrogen™ Supplier No. PA552148
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ERVEELEENI SHLSEKLQDT ENEAMSKIVE LEKQLMQRNK ELDVVREIYK DANTQVHTLR KMVKEKEEAI QRQSTLEKKI HELEKQGTIK IQKKGDGDIA ILPVVASGTL SMGSEVVAGN SVGP Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.

Formin-like protein 2 is a cytoplasmic phosphoprotein belonging to the formin homology domain containing protein family and has a DAD (diaphanous autoregulatory domain), FH2 (formin homology 2) domain, and GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. The exact function of FMNL2 is yet to be known but reports suggest that it may have a role in the Wnt signaling pathway. Formin-related proteins are also known to play an important role in morphogenesis, cytokinesis and cell polarity. Several alternatively spliced transcript variants have been described but their full-length nature is not yet determined. It is also known to be associated with a diffuse-type gastric cancer, breast cancer, chondrosarcoma, melanoma, and glioblastoma. FMNL2 might be implicated in polarity control, invasion, migration or metastasis through actin filament nucleation and may be regulated by Rho family GTPase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FMNL2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FMNL2
Gene Accession No. Q96PY5
Gene Alias 5430425K04Rik; FHOD2; FMNL2; formin homology 2 domain containing 2; formin homology 2 domain-containing protein 2; formin like 2; formin-like 2; formin-like domain containing protein MAN; formin-like protein 2; Kiaa1902; Man; protein Man
Gene Symbols FMNL2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FMNL2. Recombinant protein control fragment (Product #RP-88596).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114793
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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