FMR1 Monoclonal Antibody (OTI2C3), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-5013	100 μL
50-254-0407	30 μL

Catalog No. 50-167-5013 Supplier OriGene Supplier No. TA504293

Description

Mouse Monoclonal Antibody

FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Specifications

• Antigen: FMR1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2C3
• Concentration: 0.96 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: FMR1
• Gene Accession No.: P35922, Q06787, Q80WE1
• Gene Alias: FMRP, FRAXA, POF, POF1
• Gene Symbols: FMR1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 26-279 of human FMR1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14265, 2332, 24948, 481070
• Target Species: Canine, Human, Mouse, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a