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Invitrogen™ FOLR2 Monoclonal Antibody (EM-35), PE
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Catalog No. PIMA528551
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100 μg
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PIMA528551 100 μg
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Catalog No. PIMA528551 Supplier Invitrogen™ Supplier No. MA528551
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Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.

FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
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Specifications

Antigen FOLR2
Applications Flow Cytometry
Classification Monoclonal
Clone EM-35
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene FOLR2
Gene Accession No. P14207
Gene Alias BETA-HFR; FBP; FBP/PL-1; Fbp2; folate binding protein; folate binding protein 2; folate receptor 2; folate receptor 2 (fetal); folate receptor beta; folate receptor, beta; folate receptor, fetal/placental; Folate-binding protein 2; folate-binding protein, fetal/placental; Folbp2; Folbp-2; FOLR2; FR-beta; FR-P3; placental folate-binding protein
Gene Symbols FOLR2
Host Species Mouse
Immunogen BW5147alpha,beta- cells.
Purification Method Size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2350
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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