Forskolin, 98+%, 50 mg, Thermo Scientific Chemicals PROMO

Description

Forskolin, CAS # 66575-29-9, is a diterpenoid compound isolated from Indian Coleus that acts as a strong activator of the adenylate cyclase system.

General Description

• Forskolin is a diterpenoid and cyclic ketone, found naturally as a plant metabolite
• It is a protein kinase A agonist and a cyclic ketone
• Forskolin is an antihypertensive and muscle relaxant, it can also promote the release of pituitary hormones and prevent platelet aggregation

Application

• Forskolin assists in neuron differentiation in vitro
• Useful for studies of cell metabolism and development, there is some evidence of its usefulness in the study of glaucoma
• It is intended for cell culture and biochemistry applications

Specifications

Chemical Identifiers

• CAS: 66575-29-9
• Molecular Formula: C22H34O7
• Molecular Weight (g/mol): 410.507 g/mol
• MDL Number: MFCD00082317
• InChI Key: OHCQJHSOBUTRHG-KGGHGJDLSA-N
• Synonym: forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish
• PubChem CID: 47936
• ChEBI: CHEBI:42471
• IUPAC Name: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate
• SMILES: CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O

• Color: White
• Quantity: 50 mg
• Beilstein: 1692716
• Merck Index: 14,2476
• Solubility Information: Soluble in ethanol,dimethylsulfoxide and chloroform; Insolule in Water.
• Formula Weight: 410.51 g/mol
• Percent Purity: ≥98%
• Physical Form: Solid
• Chemical Name or Material: Forskolin

Safety and Handling

Hazard Category	H312
Hazard Statement	GHS H Statement: H315-H319-H335. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P280-P302+P352-P312-P363-P501c
EINECSNumber	266-410-9
RTECSNumber	QL6150000
TSCA	No
Recommended Storage	Store at -20°C

RUO – Research Use Only