Invitrogen™ FOXA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527158

Catalog No. PIPA527158

Description

Recommended positive controls: A431, H1299, HeLa, HepG2. Predicted reactivity: Mouse (100%), Rat (100%), Japanese Medaka (100%), Chicken (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin. They also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: FOXA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOXA2
• Gene Alias: FKHL20; forkhead box A2; forkhead box protein A2; Foxa2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3beta; HNF3B; Hnf-3b; HNF3beta; HNF-3BETA; HNF-3-beta; HNF3-beta; MGC19807; putative; RONU; TCF3B; TCF-3B; transcription factor; transcription factor 3B; transcription factor Foxa2; WHN
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15376, 3170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P35583, Q9Y261
• Gene Symbols: FOXA2
• Immunogen: Synthetic peptide corresponding to a region within amino acids 397 and 457 of FOXA2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov