Invitrogen™ FOXB1/FOXB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101247

Catalog No. PIPA5101247

Description

Antibody detects endogenous levels of total FOXB1/2.

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Specifications

• Antigen: FOXB1/FOXB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOXB2
• Gene Alias: bA159H20.4; C43; Fkh4; Fkh5; forkhead box B1; forkhead box B1a; forkhead box B1b; forkhead box B2; forkhead box protein B1; Forkhead box protein B2; forkhead homolog 4; Foxb1; Foxb1a; Foxb1b; FOXB2; Hfh-e5.1; HFKH-5; mesoderm/mesenchyme forkhead 3; Mf3; Transcription factor FKH-4; transcription factor FKH-5; Twh
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14240, 27023, 442425, 64290
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5VYV0, Q64732, Q64733, Q99853
• Gene Symbols: FOXB1, FOXB2
• Immunogen: A synthesized peptide derived from human FOXB1(Accession Q99853), corresponding to amino acid residues P293-H325.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG