Invitrogen™ FOXR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599625

Catalog No. PIPA599625

Description

Antibody detects endogenous levels of total FoxR1.

The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 amino acids. FOX transcription factors play roles in determining cell fate during early development. FOXR1 (forkhead box protein R1), also known as FOXN5 (forkhead box protein N5) or DLNB13, is a 292 amino acid nuclear protein that belongs to the FOX family and contains one forkhead DNA-binding domain. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR1 may be involved the development of certain invasive carcinomas.

Specifications

• Antigen: FOXR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Foxr1
• Gene Alias: DLNB13; Forkhead box protein N5; forkhead box protein R1; forkhead box R1; forkhead box R1 variant 1; forkhead box R1 variant 2; Foxn5; FOXR1; Gm1115
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 283150, 315601, 382074
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3UTB7, Q6PIV2
• Gene Symbols: Foxr1
• Immunogen: A synthesized peptide derived from human FOXR1(Accession Q6PIV2), corresponding to amino acid residues F231-S281.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG