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Invitrogen™ FPR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141398

Catalog No. 01-675-527


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Description

Description

Suggested positive control: human liver protein, liver lysate.

FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeleton, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FPR1
Polyclonal
Unconjugated
FPR1
fMet-Leu-Phe receptor; fMLF-R; FMLP; fMLP receptor; formyl peptide receptor 1; FPR; Fpr receptor; FPR1; FPR-1; lipoxin A4 receptor; LXA4R; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor
Rabbit
Antigen affinity chromatography
RUO
14293, 2357
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1.0 mg/mL
PBS with 0.02% sodium azide
P21462, P33766
FPR1
Synthetic peptide corresponding to residues 176-190 of humanFPR1.
100 μg
Primary
Human, Mouse, Monkey
Antibody
IgG
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