Invitrogen™ Fra1 Monoclonal Antibody (OTI12F9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524973

Catalog No. PIMA524973

Description

Fra1 Monoclonal Antibody for Western Blot, IHC (P)

The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

Specifications

• Antigen: Fra1
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P15407
• Gene Symbols: FOSL1
• Immunogen: Full-length protein expressed in 293T cell transfected with human FOSL1 expression vector.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI12F9
• Conjugate: Unconjugated
• Gene: FOSL1
• Gene Alias: AW538199; FOS like 1, AP-1 trancription factor subunit; FOS like 1, AP-1 transcription factor subunit; FOS like antigen 1; Fosl1; FOS-like antigen 1; FOS-like antigen-1; fos-related antigen 1; FRA; Fra1; fra-1; HGNC:13718; LOW QUALITY PROTEIN: fos-related antigen 1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8061
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid