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FSHR Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 226651AP

Catalog No. 50-173-3916


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Description

Description

Follicle-Stimulating Hormone Receptor (FSHR) expression has been reported in ovary, uterus, and testis. ESTs have been isolated from testis libraries. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.
Specifications

Specifications

FSHR
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P23945, P35378
Follitropin receptor, FSH R, FSHR, FSHRO, LGR1, ODG1
Rabbit
IgG
150 μL
-20°C
Primary
14309, 2492
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
FSHR
Liquid
Fshr
FSHR Fusion Protein Ag18158
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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