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Tocris Bioscience™ FTBMT
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Catalog No. 67845
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25 mg
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Catalog No. Quantity
67-845 5 mg
67-842-5 25 mg
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Catalog No. 67-845 Supplier Tocris Bioscience™ Supplier No. 6784/5
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Description

Potent and selective GPR52 agonist; orally bioavailable and BBB permeable

FTBMT (also known as TP 024) is a potent and selective GPR52 agonist (EC50 = 75 nM, Emax = 122%), which is selective for GPR52 over a panel of 98 targets including D1, D2, AMPA and NMDA. FTBMT suppresses methamphetamine-induced hyperlocomotion in mice, and inhibits MK-801 -induced hyperactivity (model for acute psychosis), without causing catalepsy in mice. This compound is orally bioavailable and brain penetrant.

Specifications

Chemical Name or Material 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide
CAS 1358575-02-6
Quantity 5 mg
Molecular Formula C19H16F4N4O
Formula Weight 392.35
Purity 98%
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