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Invitrogen™ FTO Polyclonal Antibody
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Catalog No. PIPA585698
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100 μL
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PIPA585698 100 μL
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Catalog No. PIPA585698 Supplier Invitrogen™ Supplier No. PA585698
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (83%), Rat (83%), Pig (85%), Rabbit (88%). Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, 293T, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FTO
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Fto
Gene Accession No. Q2A121, Q9C0B1
Gene Alias AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Gene Symbols Fto
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human FTO. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291905, 79068
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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