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Invitrogen™ FZD7 Polyclonal Antibody
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Catalog No. PIPA532771
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50 μg
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PIPA532771 50 μg
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Catalog No. PIPA532771 Supplier Invitrogen™ Supplier No. PA532771
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Rabbit, Opossum (100%); Platypus (94%); Chicken, Xenopus (89%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FZD7
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene FZD7
Gene Accession No. O75084, Q61090
Gene Alias frizzled 7, seven transmembrane spanning receptor; frizzled class receptor 7; frizzled family receptor 7; frizzled homolog 7; frizzled homolog 7 (Drosophila); Frizzled, drosophila, homolog of, 7; frizzled-7; Fz7; Fz-7; FZD7; FzE3; hFz7; LOC100360552; mFz7; rCG22430-like; rizzled 7
Gene Symbols FZD7
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide from C-terminus of human FZD7 / Frizzled 7.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100360552, 100766658, 103348917, 14369, 488478, 524255, 8324
Target Species Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Hamster, Bat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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