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Invitrogen™ FZD8 Polyclonal Antibody
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Catalog No. PIPA5111669
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100 μL
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PIPA5111669 100 μL
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Catalog No. PIPA5111669 Supplier Invitrogen™ Supplier No. PA5111669
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QCRAPMVSVS SERHPLYNRV KTGQIANCA Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FZD8
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Fzd8
Gene Accession No. Q9H461
Gene Alias frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046
Gene Symbols Fzd8
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human FZD8. Recombinant protein control fragment (Product #RP-107796).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8325
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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