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G10, >98%, Tocris Bioscience™

Catalog No. 594410
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Catalog No. Quantity
59-441-0 10 mg
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Catalog No. 59-441-0 Supplier R&D Systems Supplier No. 5944/10
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Description

Activator of STING-dependent signaling

Activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts. Exhibits no effect on NF-κB signaling. Blocks viral replication in vitro.

Chemical Identifiers

CAS 702662-50-8
Molecular Formula C21H16ClFN2O3S
Molecular Weight (g/mol) 430.878
InChI Key NAGKYJATVFXZKN-UHFFFAOYSA-N
Synonym sting agonist-1, 4-2-chloro-6-fluorobenzyl-n-furan-2-ylmethyl-3-oxo-3,4-dihydro-2h-benzo b 1,4 thiazine-6-carboxamide, 4-2-chloro-6-fluorophenyl methyl-n-2-furanylmethyl-3,4-dihydro-3-oxo-2h-1,4-benzothiazine-6-carboxamide, 4-2-chloro-6-fluorophenyl methyl-n-furan-2-ylmethyl-3-oxo-1,4-benzothiazine-6-carboxamide, 4-2-chloro-6-fluorophenyl methyl-n-furan-2-ylmethyl-3-oxo-3,4-dihydro-2h-1,4-benzothiazine-6-carboxamide
PubChem CID 5077622
IUPAC Name 4-[(2-chloro-6-fluorophenyl)methyl]-N-(furan-2-ylmethyl)-3-oxo-1,4-benzothiazine-6-carboxamide
SMILES C1C(=O)N(C2=C(S1)C=CC(=C2)C(=O)NCC3=CC=CO3)CC4=C(C=CC=C4Cl)F

Specifications

Linear Formula C21H16ClFN2O3S
Quantity 10 mg
Solubility Information Soluble to 100mM in DMSO
Formula Weight 430.88
Chemical Name or Material 4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-car
Grade >98%

Safety and Handling

Recommended Storage Store at −20°C
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