Invitrogen™ G6PD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527359

Catalog No. PIPA527359

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Rat (93%), Xenopus laevis (82%), Rabbit (95%), Sheep (92%), Rhesus Monkey (99%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: G6PD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: G6PD
• Gene Alias: G28A; G6PD; G6PD1; G6pd-1; G6pdx; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase; glucose-6-phosphate dehydrogenase X-linked; Gpdx
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14381, 24377, 2539
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.81 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P05370, P11413, Q00612
• Gene Symbols: G6PD, G6pdx
• Immunogen: Recombinant fragment corresponding to a region within amino acids 237 and 508 of Human G6PD.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG