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Invitrogen™ G6PD Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA527359
Description
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Rat (93%), Xenopus laevis (82%), Rabbit (95%), Sheep (92%), Rhesus Monkey (99%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Specifications
G6PD | |
Polyclonal | |
Unconjugated | |
G6PD | |
G28A; G6PD; G6PD1; G6pd-1; G6pdx; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase; glucose-6-phosphate dehydrogenase X-linked; Gpdx | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
14381, 24377, 2539 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.81 mg/mL | |
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
P05370, P11413, Q00612 | |
G6PD, G6pdx | |
Recombinant fragment corresponding to a region within amino acids 237 and 508 of Human G6PD. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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