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Invitrogen™ GABRA2 Monoclonal Antibody (N399/19), FITC
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Catalog No. PIMA545726
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100 μg
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PIMA545726 100 μg
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Catalog No. PIMA545726 Supplier Invitrogen™ Supplier No. MA545726
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Description

Mouse Monoclonal Antibody

A 1:100 dilution of MA5-45726 was sufficient for detection of GABA-A R, Alpha2 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 55kDa. Does not cross-react with GABA-A Receptor Alpha1. This antibody was formerly sold as clone S399-19.

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GABRA2
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N399/19
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
Gene GABRA2
Gene Accession No. P23576, P26048, P47869
Gene Alias C630048P16Rik; FLJ97076; GABA(A) receptor; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAARalpha2; Gabra2; Gabra-2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; gamma-aminobutyric acid receptor subunit alpha-2; gamma-aminobutyric acid type A receptor alpha2 subunit
Gene Symbols GABRA2
Host Species Mouse
Immunogen Fusion protein amino acids 350-385 (Cytoplasmic C-terminus) of rat GABA-A Receptor Alpha2.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14395, 2555, 289606
Target Species Human, Mouse, Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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