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TARGETMOL CHEMICALS INC G36 10MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T22794

Encompass_Preferred

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17(beta)-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM respectively). G36 has no detectable binding activity to either ER(alpha) or ER(beta). G36 blocks the activation of PI3K or calcium mobilization triggered by estrogen through GPER and it suppresses ERK activation by estrogen or G-1 but not by EGF. G-36 can be used in combination with GPER-selective agonists like G-1 to distinguish the roles of GPER from those of ER(alpha) and ER(beta) in complex biological systems. purity: 99%

Catalog No. 50-257-7181


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