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Galectin-3 Mouse anti-Human, Mouse, Rat, Clone: 1C1B2, Proteintech
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Catalog No. 501736309 Shop All Proteintech Group Inc Products
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50-173-6309 150 μL
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Catalog No. 50-173-6309 Supplier Proteintech Group Inc Supplier No. 602071IG150UL
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Mouse Monoclonal Antibody

The monoclonal antibody B2C10 reacts with galectin-3, a 30 kDa protein. Galectin-3 is a member of the galectin family. The protein is compose of three domains: a small amino-terminal domain, a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal domain containing repeating elements. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. The expression is also affected by neoplastic transformation: up-regulated in certain types of lymphomas and thyroid carcinoma, while down-regulated in other types of maligcies, such as colon, breast, ovarian and uterine carcinomas.

Specifications

Antigen Galectin-3
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1C1B2
Concentration 0.83 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LGALS3
Gene Accession No. P08699, P16110, P17931
Gene Alias 35 kDa lectin, CBP 35, CBP35, Gal 3, GAL3, Galactose specific lectin 3, Galactoside binding protein, GALBP, Galectin 3, Galectin-3, GALIG, IgE binding protein, L 31, Laminin binding protein, Lectin L 29, LGALS2, LGALS3, Mac 2 antigen, MAC2
Gene Symbols Lgals3
Host Species Mouse
Immunogen Galectin-3 Fusion Protein Ag6753
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16854, 3958, 83781
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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