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Tocris Bioscience™ Gap19
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Catalog No. 53531
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53-531 1 mg
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Catalog No. 53-531 Supplier Tocris Bioscience™ Supplier No. 5353/1
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Cx43 hemichannel blocker

Gap19 is a selective connexin 43 (Cx43) hemichannel blocker; has no effect on gap junction coupling or Panx-1 channels. Reduces mitochondrial potassium influx in cardiomyocytes and attenuates glutamate-triggered ATP release in primary astrocytes. Modestly reduces infarct size in a mouse ischemia model.

Specifications

Purity 0.95
Description Gap19
Molecular Weight (g/mol) 1161.45
Product Type Gap19
Quantity 1 mg
Sequence Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys

For Research Use Only

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