GAPDHS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-9104	Proteintech Group Inc 139371AP150UL	150 μL

Description

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. While GAPDH has long been recognized as playing an integral role in glycolysis, additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the beta-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.

Specifications

• Antigen: GAPDHS
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O14556, Q64467, Q9ESV6
• Gene ID (Entrez): 14447, 26330, 66020
• Immunogen: GAPDHS Fusion Protein Ag4988
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GAPDHS

• Concentration: 0.43 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: GAPD2, GAPDH 2, GAPDH2, GAPDHS, GAPDS, HSD 35
• Gene Symbols: Gapdhs
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody