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Invitrogen™ GATAD2A Polyclonal Antibody
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Catalog No. 01675595
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Catalog No. Quantity
01-675-595 200 μL
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Catalog No. 01-675-595 Supplier Invitrogen™ Supplier No. PA141241
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Description

Rabbit Polyclonal Antibody

Suggested positive control: HeLa or RAW.

GATAD2A is a gene encoding a protein that functions as a subunit of the nucleosome remodeling and deacetylase (NuRD) complex, which plays a crucial role in chromatin remodeling and gene expression regulation. Located on the human chromosome, GATAD2A contains proline-rich PPPL theta motifs that facilitate interactions with MYND domains in proteins such as ZMYND8, distinguishing it from its paralog GATAD2B. This gene is important for various cellular processes, particularly during neural development, where it participates in modulating chromatin structure through histone deacetylation and ATP-dependent remodelings, like those mediated by NuRD. Moreover, GATAD2A has been implicated in certain neurodevelopmental disorders, suggesting its distinct functional roles in cellular contexts. Additionally, research has identified circular RNA variants of GATAD2A, which have been shown to influence viral replication, indicating its broader impact on cellular function beyond chromatin modification.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GATAD2A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene GATAD2A
Gene Accession No. Q86YP4, Q8CHY6
Gene Alias 1110066C11Rik; BC031407; C80248; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; GATAD2A; Hp66alpha; MGC29315; MGC36975; p66 alpha; p66a; p66alpha; RGD1310596; transcriptional repressor p66 alpha; Transcriptional repressor p66-alpha
Gene Symbols GATAD2A
Host Species Rabbit
Immunogen Synthetic peptide corresponding to aa 137-150 of mouse p66a.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234366, 290669, 54815
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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