Invitrogen™ Gatralimab Chimeric Recombinant Human Monoclonal Antibody

Catalog No.	Quantity
PIMA542273	100 μg

Catalog No. PIMA542273 Supplier Invitrogen™ Supplier No. MA542273

Description

Human Recombinant Monoclonal Antibody

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Gatralimab is a biosimilar that targets CD52. Human CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a glycoprotein found in the male reproductive tract and immune cells. It is abundantly expressed on the surface of nearly all human peripheral blood lymphocytes. The CD52 antigen is Gpi-anchored membrane receptor that consists of a small 12 amino acid peptide attached to a large N-linked carbohydrate group. CD52 is a potent target for inducing cytolysis of mature lymphocytes. Alemtuzumab, a humanized monoclonal antibody targeting CD52, is used as an immunomodulatory drug for the treatment of chronic lymphocytic leukemia, T cell lymphomas, multiple sclerosis, and other diseases.

Specifications

• Antigen: Gatralimab Chimeric
• Applications: ELISA, SDS-Page
• Classification: Recombinant Monoclonal
• Concentration: 4.47 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.5
• Gene Alias: GZ-402668
• Host Species: Human
• Immunogen: Human CD52.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ
• Target Molecule: Chemical