Invitrogen™ GATSL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598349

Catalog No. PIPA598349

Description

GATSL2 Polyclonal Antibody for Western Blot, ELISA

Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

Specifications

• Antigen: GATSL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CASTOR2
• Gene Alias: CASTOR2; Cellular arginine sensor for mTORC1 protein 2; Cytosolic arginine sensor for mTORC1 subunit 2; GATL2; GATS protein like 2; GATS protein-like 1; GATS protein-like 2; GATSL1; GATSL2; GATS-like protein 1; GATS-like protein 2
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 729438
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.71 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: A6NHX0
• Gene Symbols: CASTOR2
• Immunogen: Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov