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Invitrogen™ GATSL2 Polyclonal Antibody
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Catalog No. PIPA598349
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PIPA598349 100 μL
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Catalog No. PIPA598349 Supplier Invitrogen™ Supplier No. PA598349
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Rabbit Polyclonal Antibody

GATSL2 Polyclonal Antibody for Western Blot, ELISA

Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GATSL2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene CASTOR2
Gene Accession No. A6NHX0
Gene Alias CASTOR2; Cellular arginine sensor for mTORC1 protein 2; Cytosolic arginine sensor for mTORC1 subunit 2; GATL2; GATS protein like 2; GATS protein-like 1; GATS protein-like 2; GATSL1; GATSL2; GATS-like protein 1; GATS-like protein 2
Gene Symbols CASTOR2
Host Species Rabbit
Immunogen Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 729438
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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