Tocris Bioscience™ GBR 12909 dihydrochloride
Selective DA uptake inhibitor; also σ ligand
Supplier: Tocris Bioscience™ 0421/50
DescriptionGBR 12909 dihydrochloride is a potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has >100-fold lower affinity for the noradrenaline and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
|Soluble to 50mM in DMSO|
|Observed MW: 523.49|
Safety and Handling
Recommended Storage : Desiccate at Room Temperature
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For Research Use Only