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Invitrogen™ GCLC Recombinant Rabbit Monoclonal Antibody (0X1H3)
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Catalog No. PIMA535522
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100 μL
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PIMA535522 100 μL
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Catalog No. PIMA535522 Supplier Invitrogen™ Supplier No. MA535522
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Description

GCLC Recombinant Rabbit Monoclonal Antibody (ARC1065)

GCLC Recombinant Monoclonal Antibody for Western Blot

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCLC
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 0X1H3
Concentration 1.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Gclc
Gene Accession No. P19468
Gene Alias cb1049; D9Wsu168e; EGK_15023; fe36e11; gamma GCS-HS; gamma-ECS; Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase heavy subunit; GCL; Gclc; GCS; GCS heavy chain; Ggcs-hs; GLCL; GLCLC; GLCL-H; glutamate-cysteine ligase catalytic subunit; Glutamate--cysteine ligase catalytic subunit; glutamate-cysteine ligase, catalytic subunit; Glutamylcysteine gamma synthetase light chain; wu:fe36e11
Gene Symbols Gclc
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 538-637 of human GCLC (P48506).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25283
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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