Invitrogen™ GCN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517523

Catalog No. PIPA517523

Description

It is not recommended to aliquot this antibody.

EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation. Mutations in the gene lead to pulmonary vennocclusive disease 2.

Specifications

• Antigen: GCN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF2AK4
• Gene Alias: 2610011M03; EIF2AK4; eIF-2-alpha kinase GCN2; eukaryotic translation initiation factor 2 alpha kinase 4; eukaryotic translation initiation factor 2-alpha kinase 4; Gcn2; GCN2 eIF2alpha kinase; GCN2-like protein; general control nonderepressible 2; Kiaa1338; mGCN2; PVOD2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 114859, 27103, 440275
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 61 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: D4A7V9, Q9P2K8, Q9QZ05
• Gene Symbols: EIF2AK4
• Immunogen: Synthetic peptide corresponding to sequence near the amino terminus of human GCN2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG