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Invitrogen™ GCN5 Monoclonal Antibody (S.775.4)
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Catalog No. PIMA514884
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100 μL
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PIMA514884 100 μL
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Catalog No. PIMA514884 Supplier Invitrogen™ Supplier No. MA514884
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the related PCAF protein.

SAGA (Spt-Ada-Gen5 histone acetyltransferase complex) is a histoneacetylase complex which has Gcn5p as catalyst subunit and functions overlapping with the fundamental transcription factor TFIID which has Taf1p as catalyst subunit. However, SAGA and TFIID have different allotment and each accomplishes the important role in the transcription for Housekeeping gene group and Stress Responding gene group. Also, SAGA is a gigantic protein complex which is composed of Ada protein group (5 kinds), TBP related protein group (4 kinds), TAF protein group (5 kinds that also pertain to TFIID), and other protein groups (>6 kinds). As its molecular function, there is the chemical modification of histone, or the recruitment by direct interaction of transcription regulating factor on DNA, or the control of transcription starting reaction by TBP. Gcn5p that show histoneacetylase activity is one kind of the above-mentioned Ada protein group, and in the case of budding yeast it is composed of 439 amino acid residues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCN5
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone S.775.4
Concentration 134 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene KAT2A
Gene Accession No. Q92830, Q9JHD2
Gene Alias 1110051E14Rik; AAS104; ADA4; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; Gcn5l2; general control of amino acid synthesis 5-like 2; general control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2; Kat2a; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97; SWI9; YGR252W
Gene Symbols KAT2A
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the amino terminus of human GCN5L2.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14534, 2648, 303539
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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