Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ GDC 0941

Tocris Bioscience™ GDC 0941

Catalog No. 890550
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
89-055-0 50 mg
89-051-0 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. 89-055-0 Supplier Tocris Bioscience™ Supplier No. 8905/50
Only null left
Add to Cart
Add to Cart

Description

Potent pan-class I PI3 kinase inhibitor

GDC 0941 is a potent pan PI3K inhibitor of class I catalytic subunits p110α, δ, β, and γ (IC50 values are 3, 3, 33 and 75 nM, respectively). GDC 0941 inhibits the PI3K/AKT/mTOR signaling pathways and tumor cell growth in vitro and in vivo. GDC 0941 can be used in stem cell differentiation protocols to generate artery and vein endothelial cells from PSCs. GDC 0941 is orally bioavailable.

Specifications

Chemical Name or Material 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine
CAS 957054-30-7
Quantity 50 mg
Target PI 3-Kinase Inhibitors
Molecular Formula C23H27N7O3S2
Purity 98%
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.