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Invitrogen™ GDNF Polyclonal Antibody
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Catalog No. 01674407
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500 μg
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Catalog No. Quantity
01-674-407 500 μg
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Catalog No. 01-674-407 Supplier Invitrogen™ Supplier No. PA19524
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Description

Chicken Polyclonal Antibody

PA1-9524 detects GDNF in human, mouse and rat samples. PA1-9524 has been successfully used in Western blot, ELISA, and Immunohistochemistry procedures. By Western blot, PA1-9524 detects a 24 kDa protein representing GDNF. PA1-9524 immunogen is a synthetic peptide based on the human GDNF protein. Store product at 4°C for up to one week, and -20°C for long term storage.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GDNF
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene GDNF
Gene Accession No. P39905, P48540, Q07731
Gene Alias AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Gene Symbols GDNF
Host Species Chicken
Immunogen Synthetic peptide mixture based on the human GDNF protein.
Purification Method IgY fraction
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14573, 25453, 2668
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
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