Invitrogen™ GDNF Polyclonal Antibody

Chicken Polyclonal Antibody

Supplier:  Invitrogen™ PA19524

Catalog No. 01-674-407

Description

PA1-9524 detects GDNF in human, mouse and rat samples. PA1-9524 has been successfully used in Western blot, ELISA, and Immunohistochemistry procedures. By Western blot, PA1-9524 detects a 24 kDa protein representing GDNF. PA1-9524 immunogen is a synthetic peptide based on the human GDNF protein. Store product at 4ºC for up to one week, and -20ºC for long term storage.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Specifications

• Antigen: GDNF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GDNF
• Gene Alias: AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
• Host Species: Chicken
• Purification Method: IgY fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 14573, 25453, 2668
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P39905, P48540, Q07731
• Gene Symbols: GDNF
• Immunogen: Synthetic peptide mixture based on the human GDNF protein.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY