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Invitrogen™ GEF-H1 Monoclonal Antibody (GT1132)
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Catalog No. PIMA527802
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100 μL
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PIMA527802 100 μL
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Catalog No. PIMA527802 Supplier Invitrogen™ Supplier No. MA527802
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Description

Mouse Monoclonal Antibody

Positive Control: 293T, A431, HeLa, Neuro2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12, PC-12, Rat-2, 3A6 Predicted Reactivity: Dog (92%), Pig (96%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GEF-H1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone GT1132
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene ARHGEF2
Gene Accession No. Q5FVC2, Q60875, Q92974
Gene Alias AA408978; ARHGEF2; CG10188; CG10188-PA; CG10188-PB; CG10188-PC; cyst; cyst-PA; cyst-PB; cyst-PC; cysts; DKFZp547L106; DKFZp547P1516; Dmel\CG10188; Dmel_CG10188; FLJ45440; GEF; GEFH1; GEF-H1; Guanine nucleotide exchange factor H1; Kiaa0651; Lbcl1; LBC'S first cousin; Lfc; LFP40; Lymphoid blast crisis-like 1; microtubule-regulated Rho-GEF; mKIAA0651; oncogene LFC; OTTHUMP00000018855; P40; Proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; rho guanine nucleotide exchange factor 2-like protein; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2; rhobin
Gene Symbols ARHGEF2
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human GEF-H1. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16800, 310635, 9181
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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