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Invitrogen™ GeneArt™ CRISPR Nuclease mRNA

Superior quality GeneArt CRISPR Nuclease mRNA is formulated to improve product performance.

Supplier: Invitrogen™ A29378

Catalog No. A29378

$416.00 / Each of 1

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For research use only. Not for use in diagnostic procedures.

Includes: 1 vial (15 μg) GeneArt Platinum Cas9 Protein

Description

GeneArt CRISPR Nuclease mRNA is formulated for superior quality and improved product performance. The mRNA format is ready to transfect and eliminates time-consuming cloning required when using CRISPR vector systems.

This wild-type Cas9 mRNA has two nuclear localization signals (NLSs) which has been shown to be more efficient at targeting the Cas9 protein to the nucleus (1).

The mRNA format is ready to transfect and eliminates time-consuming cloning required when using CRISPR vector systems. Cas9 mRNA is co-transfected with a target-specific guide RNA (gRNA) to direct the Cas9 protein to the intended genome locus to create a double-stranded break.

The complete RNA format is a smaller payload than plasmid-based Cas9 systems for improved delivery into the cell and better genome editing efficiency. Additionally, the Cas9 mRNA can be used in multiplex approaches with more than one gRNA. Use this approach to determine which gRNA sequence works best for a particular target or to edit multiple genomic loci with one transfection. Use our GeneArt Precision gRNA Synthesis Kit or GeneArt CRISPR Strings to make your target specific gRNA.

GeneArt CRISPR Nuclease Vector product features include:

Fewer steps with no annealing, cloning, or vector required for screening experiments
Smaller payload for improved delivery and better genome editing efficiency
T7 promoter option to improve cleavage in difficult to transfect cells
Easier for multiplexed gene editing
Easier delivery by microinjection

For research use only. Not for use in diagnostic procedures.

Certifications

CoA

Recommended Storage

Store in ultra-cold freezer (-68 to -85°C).
Product may be stored short-term in freezer (-5 to -30°C).

Specifications

Content And Storage	1 vial CRISPR Nuclease mRNA Store in ultra-cold freezer (-68° to -85°C). Product may be stored short-term in freezer (-5° to -30°C).
Final Product Type	RNA
Product Type	Crispr Nuclease MRNA
Shipping Condition	Dry Ice

Format	Tube
Product Line	GeneArt™
Quantity	15 μg
Volume (Metric)	15 μg

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For Research Use Only. Not for use in diagnostic procedures.

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