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GFI1 Mouse anti-Human, Clone: OTI6C10, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF807139

Encompass_Preferred

Catalog No. 50-166-8132


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Gfi-1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.
Specifications

Specifications

GFI1
Monoclonal
Unconjugated
GFI1
GFI-1, GFI1A, SCN2, ZNF163
Mouse
Affinity Chromatography
RUO
2672
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI6C10
PBS with 8% trehalose and no preservative; pH 7.3
Q99684
GFI1
Full length human recombit protein of human GFI1 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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