Invitrogen™ GFM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550026

Catalog No. PA550026

Description

The antibody detects endogenous levels of total GFM2 protein.

GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.

Specifications

• Antigen: GFM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gfm2
• Gene Alias: 6530419G12Rik; A930009M04Rik; EFG2; EF-G2mt; EF-G2mt {ECO:0000255; Elongation factor G 2, mitochondrial; elongation factor G 2, mitochondrial {ECO:0000255; Elongation factor G2; G elongation factor; G elongation factor mitochondrial 2; G elongation factor, mitochondrial 2; GFM2; HAMAP-Rule:MF_03059}; hEFG2; mEF-G 2; mEF-G 2 {ECO:0000255; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; MRRF2; MST027; MSTP027; RGD1309854; ribosome-releasing factor 2, mitochondrial; ribosome-releasing factor 2, mitochondrial {ECO:0000255; RRF2; RRF2mt; RRF2mt {ECO:0000255
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 320806, 84340
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8R2Q4, Q969S9
• Gene Symbols: Gfm2
• Immunogen: Synthesized peptide derived from internal of human GFM2 (aa 661-710).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG