Invitrogen™ GFR alpha-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA118399

Catalog No. 01-670-650

Description

Reconstitute in 100 μL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

Specifications

• Antigen: GFR alpha-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GFRA2
• Gene Alias: GDNF family receptor alpha 2; GDNF family receptor alpha-2; GDNF re; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; Gdnfrb; GDNFR-beta; Gfra2; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor family receptor alpha 2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; neurturin receptor alpha; NRTNR-alpha; NTNRA; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; RETL2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2; tyrosine kinase receptor ligand 2
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Frozen), Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with no preservative
• Gene Accession No.: O00451
• Gene Symbols: GFRA2
• Immunogen: Synthetic peptide corresponding to residues P(376) R V E K T P S L P D D L S D(390) of human GFR alpha-2.
• Regulatory Status: RUO
• Gene ID (Entrez): 25136, 2675
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov