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Invitrogen™ GFRAL Polyclonal Antibody
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Catalog No. PIPA547769
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100 μg
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PIPA547769 100 μg
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Catalog No. PIPA547769 Supplier Invitrogen™ Supplier No. PA547769
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Description

Sheep Polyclonal Antibody

In direct ELISA, less than 1% cross-reactivity with recombinant mouse (rm) GFR alpha -3 and rmGFR alpha -4 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen GFRAL
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative; pH 7.4
Gene GFRAL
Gene Accession No. Q6SJE0
Gene Alias AY457637; bA360D14.1; C6orf144; GDNF family receptor alpha like; GDNF family receptor alpha-like; GDNF receptor alpha-like; GFRAL; Gral; IVFI9356; RGD1565220; UNQ9356; UNQ9356/PRO34128
Gene Symbols GFRAL
Host Species Sheep
Immunogen CHO-derived recombinant mouse GFR alpha-like isoform A Gln20-Gly349.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 404194
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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