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Invitrogen™ GGH Polyclonal Antibody
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Catalog No. PIPA5101599
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100 μL
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PIPA5101599 100 μL
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Catalog No. PIPA5101599 Supplier Invitrogen™ Supplier No. PA5101599
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GGH.

Gamma-Glutamyl hydrolase (GGH) is a homodimeric protein that catalyzes the cleavage of the gamma-glutamyl chain of folylpoly-gamma-glutamyl substrates and is a central enzyme in folyl and antifolyl poly-gamma-glutamate metabolism. The activities of the baculovirus-expressed enzyme and the enzyme from HL-60 cells were similar on methotrexate polyglutamates. GGH is expressed in a variety of human tumors and correlates with poor prognosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GGH
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Ggh
Gene Accession No. Q92820, Q9Z0L8
Gene Alias conjugase; FGPH; folylpolyglutamate hydrolase; gamma-GH; gamma-glutamyl hydrolase; gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); Gamma-Glu-X carboxypeptidase; GGH; GH
Gene Symbols Ggh
Host Species Rabbit
Immunogen A synthesized peptide derived from human GGH(Accession Q92820), corresponding to amino acid residues L255-T305.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14590, 8836
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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