Invitrogen™ Ghrelin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA11070

Catalog No. APP1070

Description

PA1-1070 detects Obestatin in mouse and rat samples. This product does not detect endogenous levels of the hormone in rat stomach. PA1-1070 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~2.5 kDa protein representing synthetic Obestatin. The PA1-1070 immunogen is a synthetic peptide corresponding to residues F(1) N A P F D V G I K L S G A Q Y Q Q H G R A L(23) of the rat Obestatin gene. This sequence is conserved in mouse and only one amino acid residue difference in human. This peptide (Cat. # PEP-290) is available for use in neutralization and control experiments.

GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.

Specifications

• Antigen: Ghrelin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GHRL
• Gene Alias: 2210006E23Rik; AMCBX1; Appetite-regulating hormone; appetite-regulating hormone; uncharacterized protein LOC58991; exon 2- and 3-deleted preproghrelin; exon 2-deleted preproghrelin; FIP3; FIP-3; Fip3p; Ghr; Ghrelin; ghrelin 27; ghrelin 28; ghrelin and obestatin prepropeptide; ghrelin precursor; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; Ghrelin-27; Ghrelin-28; ghrelin-like protein; GHRL; Growth hormone secretagogue; growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; m46; Motilin-related peptide; MTLRP; MTLRPAP; NEMO; Obestatin; Obestatin-13; Obestatin-23; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; proghrelin; Protein M46; UNQ524/PRO1066
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51738, 58991, 59301
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: Q9EQX0, Q9QYH7, Q9UBU3
• Gene Symbols: GHRL
• Immunogen: Synthetic peptide corresponding to residues F(1) N A P F D V G I K L S G A Q Y Q Q H G R A L(23) of the rat Obestatin gene.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG